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AffiliationDepartment of Epidemiology and BiostatisticsImperial College LondonLondonUnited Kingdom.

It should be noted that whilein theorytwo different sequences could have the same checksum valuethe likelihood that this would happen is extremely low.

AffiliationDepartment of Epidemiology and BiostatisticsImperial College LondonLondonUnited Kingdom.

This section is used to point to information related to entries and found in data collections other than UniProtKB.

We present here the first GWAS on circulating AAT blood levelsOur results confirm that genetic variation in the SERPINA1 gene is a strong determinant of serum AAT levelsFine mapping of SERPINA1 and subsequent stepwise regression analyses further revealed that the associations with common variants in the SERPINA locus could be attributed to rarer variants previously identified to be causally linked with AAT deficiency.

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