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FDA pregnancy category CIt is not known whether Zyloprim will harm an unborn babyTell your doctor if you are pregnant or plan to become pregnant while using this medication.

Both Zyloprim and oxipurinol are dialyzablehoweverthe usefulness of hemodialysis or peritoneal dialysis in the management of an overdose of Zyloprim is unknown.

Since the excretion of oxipurinol is similar to that of urateuricosuric agentswhich increase the excretion of urateare also likely to increase the excretion of oxipurinol and thus lower the degree of inhibition of xanthine oxidaseThe concomitant administration of uricosuric agents and Zyloprim has been associated with a decrease in the excretion of oxypurineshypoxanthine and xanthineand an increase in urinary uric acid excretion compared with that observed with Zyloprim aloneAlthough clinical evidence to date has not demonstrated renal precipitation of oxypurines in patients either on Zyloprim alone or in combination with uricosuric agentsthe possibility should be kept in mind.

Gout is a metabolic disorder which is characterized by hyperuricemia and resultant deposition of monosodium urate in the tissuesparticularly the joints and kidneysThe etiology of this hyperuricemia is the overproduction of uric acid in relation to the patient’s ability to excrete itIf progressive deposition of urates is to be arrested or reversedit is necessary to reduce the serum uric acid level below the saturation point to suppress urate precipitation.

Zyloprim is used to treat gout or kidney stonesand to decrease levels of uric acid in people who are receiving cancer treatment.

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